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FoxP3(+) regulatory CD4 T cells control the generation of functional CD8 memory

During the primary immune response, CD8 memory emerges from an environment of strong immune activation. The FoxP3(+) regulatory CD4 T-cell subset (Treg) is known as a key suppressive component of the immune system. Here we report that Tregs are required for the generation of functional CD8 memory. I...

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Detalhes bibliográficos
Main Authors: de Goër de Herve, M.G., Jaafoura, S., Vallée, M., Taoufik, Y.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Pub. Group 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3432473/
https://ncbi.nlm.nih.gov/pubmed/22871805
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms1992
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