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Cytochrome P4502E1, Oxidative Stress, JNK and Autophagy in Acute Alcohol-induced Fatty Liver

Binge alcohol drinking induces hepatic steatosis. Recent studies showed that chronic ethanol-induced fatty liver was, at least in part, CYP2E1 dependent. The mechanism of acute alcohol induced steatosis and whether CYP2E1 plays any role is still unclear. Increasing oxidative stress by alcohol can ac...

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Bibliographic Details
Main Authors: Yang, Lili, Wu, Defeng, Wang, Xiaodong, Cederbaum, Arthur I
Format: Artigo
Language:Inglês
Published: 2012
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3432162/
https://ncbi.nlm.nih.gov/pubmed/22749809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2012.06.029
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