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Intranasal exposure to manganese disrupts neurotransmitter release from glutamatergic synapses in the central nervous system in vivo
Chronic exposure to aerosolized manganese induces a neurological disorder that includes extrapyramidal motor symptoms and cognitive impairment. Inhaled manganese can bypass the blood-brain barrier and reach the central nervous system by transport down the olfactory nerve to the brain’s olfactory bul...
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Главные авторы: | , , , , , , |
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Формат: | Artigo |
Язык: | Inglês |
Опубликовано: |
2012
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Предметы: | |
Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3432160/ https://ncbi.nlm.nih.gov/pubmed/22542936 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuro.2012.04.014 |
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