Intranasal exposure to manganese disrupts neurotransmitter release from glutamatergic synapses in the central nervous system in vivo

Chronic exposure to aerosolized manganese induces a neurological disorder that includes extrapyramidal motor symptoms and cognitive impairment. Inhaled manganese can bypass the blood-brain barrier and reach the central nervous system by transport down the olfactory nerve to the brain’s olfactory bul...

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Bibliografiske detaljer
Main Authors: Moberly, Andrew H., Czarnecki, Lindsey A., Pottackal, Joseph, Rubinstein, Tom, Turkel, Daniel J., Kass, Marley D., McGann, John P.
Format: Artigo
Sprog:Inglês
Udgivet: 2012
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3432160/
https://ncbi.nlm.nih.gov/pubmed/22542936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuro.2012.04.014
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