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Sperm mRNA Transcripts Are Indicators of Sub-Chronic Low Dose Testicular Injury in the Fischer 344 Rat

Current human reproductive risk assessment methods rely on semen and serum hormone analyses, which are not easily comparable to the histopathological endpoints and mating studies used in animal testing. Because of these limitations, there is a need to develop universal evaluations that reliably refl...

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Autors principals: Pacheco, Sara E., Anderson, Linnea M., Sandrof, Moses A., Vantangoli, Marguerite M., Hall, Susan J., Boekelheide, Kim
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3432073/
https://ncbi.nlm.nih.gov/pubmed/22952946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0044280
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