Nicotine Promotes Proliferation of Human Nasopharyngeal Carcinoma Cells by Regulating α7AChR, ERK, HIF-1α and VEGF/PEDF Signaling

Nicotine, the major component in cigarette smoke, can promote tumor growth and angiogenesis, but the precise mechanisms involved remain largely unknown. Here, we investigated the mechanism of action of nicotine in human nasopharyngeal carcinoma (NPC) cells. Nicotine significantly promoted cell proli...

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Bibliographic Details
Main Authors: Shi, Dingbo, Guo, Wei, Chen, Wangbin, Fu, Lingyi, Wang, Jingshu, Tian, Yung, Xiao, Xiangsheng, Kang, Tiebang, Huang, Wenlin, Deng, Wuguo
Format: Artigo
Language:Inglês
Published: Public Library of Science 2012
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3432052/
https://ncbi.nlm.nih.gov/pubmed/22952803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0043898
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