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Biomarkers and surrogate endpoints for normal-tissue effects of radiation therapy: the importance of dose-volume effects

Biomarkers are of interest for predicting or monitoring normal tissue toxicity of radiation therapy. Advances in molecular radiobiology provide novel leads in the search for normal tissue biomarkers with sufficient sensitivity and specificity to become clinically useful. This paper reviews examples...

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Detalhes bibliográficos
Main Authors: Bentzen, Søren M., Parliament, Matthew, Deasy, Joseph O., Dicker, Adam, Curran, Walter J., Williams, Jacqueline P., Rosenstein, Barry S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3431963/
https://ncbi.nlm.nih.gov/pubmed/20171510
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijrobp.2009.08.076
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