Krüppel-associated Box (KRAB)-associated Co-repressor (KAP-1) Ser-473 Phosphorylation Regulates Heterochromatin Protein 1β (HP1-β) Mobilization and DNA Repair in Heterochromatin

The DNA damage response encompasses a complex series of signaling pathways that function to regulate and facilitate the repair of damaged DNA. Recent studies have shown that the repair of transcriptionally inactive chromatin, named heterochromatin, is dependent upon the phosphorylation of the co-rep...

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Detalhes bibliográficos
Main Authors: Bolderson, Emma, Savage, Kienan I., Mahen, Robert, Pisupati, Venkat, Graham, Mark E., Richard, Derek J., Robinson, Phillip J., Venkitaraman, Ashok R., Khanna, Kum Kum
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
DNA and Chromosomes
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3431694/
https://ncbi.nlm.nih.gov/pubmed/22715096
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.368381
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