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Excision in vitro of the DNA bound carcinogen, 4-nitroquinoline 1-oxide.

It has been shown that 4-hydroxyaminoquinoline 1-oxide, the proximate form of the carcinogen 4-nitroquinoline 1-oxide, binds covalently to the purine bases of DNA. Here we report that carcinogen-bound nucleotides can be excised from DNA by a 5' leads to 3' exonuclease associated with DNA p...

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Detalles Bibliográficos
Main Authors: Yoshida, S, Tada, M
Formato: Artigo
Idioma:Inglês
Publicado: 1976
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC343165/
https://ncbi.nlm.nih.gov/pubmed/188019
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