Excision in vitro of the DNA bound carcinogen, 4-nitroquinoline 1-oxide.
It has been shown that 4-hydroxyaminoquinoline 1-oxide, the proximate form of the carcinogen 4-nitroquinoline 1-oxide, binds covalently to the purine bases of DNA. Here we report that carcinogen-bound nucleotides can be excised from DNA by a 5' leads to 3' exonuclease associated with DNA polymerase...
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| Pubblicato in: | Nucleic Acids Res |
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| Autori principali: | , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Oxford University Press
1976
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| Accesso online: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC343165/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/188019/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/3.11.3227 |
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