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Human Serum Albumin Can Regulate Amyloid-β Peptide Fiber Growth in the Brain Interstitium: IMPLICATIONS FOR ALZHEIMER DISEASE
Alzheimer disease is a neurodegenerative disorder characterized by extracellular accumulation of amyloid-β peptide (Aβ) in the brain interstitium. Human serum albumin (HSA) binds 95% of Aβ in blood plasma and is thought to inhibit plaque formation in peripheral tissue. However, the role of albumin i...
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| Autors principals: | , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Biochemistry and Molecular Biology
2012
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3431649/ https://ncbi.nlm.nih.gov/pubmed/22718756 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.C112.360800 |
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