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Bupivacaine inhibits large conductance, voltage- and Ca(2+)- activated K(+) channels in human umbilical artery smooth muscle cells

Bupivacaine is a local anesthetic compound belonging to the amino amide group. Its anesthetic effect is commonly related to its inhibitory effect on voltage-gated sodium channels. However, several studies have shown that this drug can also inhibit voltage-operated K(+) channels by a different blocki...

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Detalhes bibliográficos
Main Authors: Martín, Pedro, Enrique, Nicolás, Palomo, Ana R. Roldán, Rebolledo, Alejandro, Milesi, Veronica
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3431591/
https://ncbi.nlm.nih.gov/pubmed/22688134
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/chan.20362
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