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Iodination as a probe for small regions of disrupted secondary structure in double-stranded DNAs.
Conditions were established where the thallium-catalyzed iodination of random coil DNA proceeded 100-200 times faster than for native DNA. This reaction was explored as a probe for localized regions of disrupted base pairs in duplex DNA. A heteroduplex was constructed between DNA fragments produced...
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| Main Authors: | , , |
|---|---|
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
1976
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| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC343158/ https://ncbi.nlm.nih.gov/pubmed/1087408 |
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