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Autocrine Adenosine Signaling Promotes Regulatory T Cell–Mediated Renal Protection
Regulatory T cells (Tregs) suppress the innate inflammation associated with kidney ischemia-reperfusion injury (IRI), but the mechanism is not well understood. Tregs express CD73, the final enzyme involved in the production of extracellular adenosine, and activation of the adenosine 2A receptor (A(2...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Society of Nephrology
2012
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3431416/ https://ncbi.nlm.nih.gov/pubmed/22835488 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2012010070 |
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