Expression of Human Paraoxonase 1 Decreases Superoxide Levels and Alters Bacterial Colonization in the Gut of Drosophila melanogaster

Paraoxonases (PON) are a family of proteins (PON1, 2 and 3) with multiple enzymatic activities. PON1 interferes with homoserine lactone-mediated quorum sensing in bacteria and with reactive oxygen species (ROS) in humans and mice. PON1 gene mutations have been linked to multiple traits, including ag...

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Detalhes bibliográficos
Main Authors: Pezzulo, Alejandro A., Hornick, Emma E., Rector, Michael V., Estin, Miriam, Reisetter, Anna C., Taft, Peter J., Butcher, Stephen C., Carter, A. Brent, Manak, J. Robert, Stoltz, David A., Zabner, Joseph
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3431398/
https://ncbi.nlm.nih.gov/pubmed/22952763
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0043777
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