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Induction of interferon by polyribonucleotides containing thiopyrimidines.
The influence of thioketo substitution in pyrimidine bases of double-stranded polynucleotides on interferon induction was investigated. The stabilizing effect of 2-thioketo substitution was reflected in the increased interferon inducing activity of poly(A-s2U) over that of poly(A-U). Poly(A-s2U) and...
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| Main Authors: | , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
1976
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| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC343133/ https://ncbi.nlm.nih.gov/pubmed/995654 |
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