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Induction of interferon by polyribonucleotides containing thiopyrimidines.

The influence of thioketo substitution in pyrimidine bases of double-stranded polynucleotides on interferon induction was investigated. The stabilizing effect of 2-thioketo substitution was reflected in the increased interferon inducing activity of poly(A-s2U) over that of poly(A-U). Poly(A-s2U) and...

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Detalles Bibliográficos
Main Authors: Reuss, K, Scheit, K H, Saiko, O
Formato: Artigo
Idioma:Inglês
Publicado: 1976
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC343133/
https://ncbi.nlm.nih.gov/pubmed/995654
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