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Drosophila melanogaster Acetyl-CoA-Carboxylase Sustains a Fatty Acid–Dependent Remote Signal to Waterproof the Respiratory System

Fatty acid (FA) metabolism plays a central role in body homeostasis and related diseases. Thus, FA metabolic enzymes are attractive targets for drug therapy. Mouse studies on Acetyl-coenzymeA-carboxylase (ACC), the rate-limiting enzyme for FA synthesis, have highlighted its homeostatic role in liver...

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Bibliographic Details
Main Authors: Parvy, Jean-Philippe, Napal, Laura, Rubin, Thomas, Poidevin, Mickael, Perrin, Laurent, Wicker-Thomas, Claude, Montagne, Jacques
Format: Artigo
Language:Inglês
Published: Public Library of Science 2012
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3431307/
https://ncbi.nlm.nih.gov/pubmed/22956916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1002925
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