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Direct Simulation of Early-Stage Sec-Facilitated Protein Translocation
Direct simulations reveal key mechanistic features of early-stage protein translocation and membrane integration via the Sec-translocon channel. We present a novel computational protocol that combines non-equilibrium growth of the nascent protein with microsecond-timescale molecular dynamics traject...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2012
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3431202/ https://ncbi.nlm.nih.gov/pubmed/22852862 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja3034526 |
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