Plasmacytoid Dendritic Cells in the Tumor Microenvironment: Immune Targets for Glioma Therapeutics

Adenovirus-mediated delivery of the immune-stimulatory cytokine Flt3L and the conditionally cytotoxic thymidine kinase (TK) induces tumor regression and long-term survival in preclinical glioma (glioblastoma multiforme [GBM]) models. Flt3L induces expansion and recruitment of plasmacytoid dendritic...

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Bibliografiske detaljer
Main Authors: Candolfi, Marianela, King, Gwendalyn D, Yagiz, Kader, Curtin, James F, Mineharu, Yohei, Muhammad, AKM Ghulam, Foulad, David, Kroeger, Kurt M, Barnett, Nick, Josien, Regis, Lowenstein, Pedro R, Castro, Maria G
Format: Artigo
Sprog:Inglês
Udgivet: Neoplasia Press Inc. 2012
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3431182/
https://ncbi.nlm.nih.gov/pubmed/22952428
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