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Gene Fusions Associated with Recurrent Amplicons Represent a Class of Passenger Aberrations in Breast Cancer

Application of high-throughput transcriptome sequencing has spurred highly sensitive detection and discovery of gene fusions in cancer, but distinguishing potentially oncogenic fusions from random, “passenger” aberrations has proven challenging. Here we examine a distinctive group of gene fusions th...

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Autori principali: Kalyana-Sundaram, Shanker, Shankar, Sunita, DeRoo, Scott, Iyer, Matthew K, Palanisamy, Nallasivam, Chinnaiyan, Arul M, Kumar-Sinha, Chandan
Natura: Artigo
Lingua:Inglês
Pubblicazione: Neoplasia Press Inc. 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3431177/
https://ncbi.nlm.nih.gov/pubmed/22952423
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