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Role of DNA-dependent protein kinase catalytic subunit in cancer development and treatment
DNA-dependent protein kinase catalytic subunit (DNA-PKcs), a key component of the non-homologous end-joining (NHEJ) pathway, is involved in DNA double-strand break repair, immunocompetence, genomic integrity, and epidermal growth factor receptor signaling. Clinical studies indicate that expression a...
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主要な著者: | , , |
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フォーマット: | Artigo |
言語: | Inglês |
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2012
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オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3431019/ https://ncbi.nlm.nih.gov/pubmed/22943041 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3978/j.issn.2218-676X.2012.04.01 |
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