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Role of DNA-dependent protein kinase catalytic subunit in cancer development and treatment

DNA-dependent protein kinase catalytic subunit (DNA-PKcs), a key component of the non-homologous end-joining (NHEJ) pathway, is involved in DNA double-strand break repair, immunocompetence, genomic integrity, and epidermal growth factor receptor signaling. Clinical studies indicate that expression a...

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Detalhes bibliográficos
Main Authors: Hsu, Feng-Ming, Zhang, Shichuan, Chen, Benjamin P.C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3431019/
https://ncbi.nlm.nih.gov/pubmed/22943041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3978/j.issn.2218-676X.2012.04.01
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