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Suppression of Inflammation in Ulcerative Colitis by Interferon-β-1a Is Accompanied by Inhibition of IL-13 Production

BACKGROUND AND AIMS: Ulcerative colitis (UC) is associated with increased IL-13 production by natural killer T cells. Taking advantage of the inhibitory actions of interferon-β on IL-13 expression, this proof-of-concept study aimed to show that decreasing IL-13 production is associated with clinical...

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Bibliographic Details
Main Authors: Mannon, Peter J., Hornung, Ronald L., Yang, Zhiqiong, Yi, Chuli, Groden, Catherine, Friend, Julia, Yao, Michael, Strober, Warren, Fuss, Ivan J.
Format: Artigo
Language:Inglês
Published: 2010
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3430969/
https://ncbi.nlm.nih.gov/pubmed/20971977
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gut.2010.226860
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