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Lower cognitive performance in healthy G2019S LRRK2 mutation carriers

OBJECTIVE: To assess cognitive abilities of healthy first-degree relatives of Ashkenazi patients with Parkinson disease (PD), carriers of the G2019S mutation in the LRRK2 gene. METHODS: In this observational study, 60 consecutive healthy first-degree relatives (aged 50.9 ± 6.2 years; 48% male; 30 G2...

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Autors principals: Thaler, Avner, Mirelman, Anat, Gurevich, Tanya, Simon, Ely, Orr-Urtreger, Avi, Marder, Karen, Bressman, Susan, Giladi, Nir
Format: Artigo
Idioma:Inglês
Publicat: Lippincott Williams & Wilkins 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3430708/
https://ncbi.nlm.nih.gov/pubmed/22914834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/WNL.0b013e3182684646
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