DaT-SPECT assessment depicts dopamine depletion among asymptomatic G2019S LRRK2 mutation carriers

Identification of early changes in Dopamine-Transporter (DaT) SPECT imaging expected in the prodromal phase of Parkinson’s disease (PD), are usually overlooked. Carriers of the G2019S LRRK2 mutation are known to be at high risk for developing PD, compared to non-carriers. In this work we aimed to st...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Artzi, Moran, Even-Sapir, Einat, Lerman Shacham, Hedva, Thaler, Avner, Urterger, Avi Orr, Bressman, Susan, Marder, Karen, Hendler, Talma, Giladi, Nir, Ben Bashat, Dafna, Mirelman, Anat
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5391020/
https://ncbi.nlm.nih.gov/pubmed/28406934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0175424
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