Vitamin K-Antagonists Accelerate Atherosclerotic Calcification and Induce a Vulnerable Plaque Phenotype

BACKGROUND: Vitamin K-antagonists (VKA) are treatment of choice and standard care for patients with venous thrombosis and thromboembolic risk. In experimental animal models as well as humans, VKA have been shown to promote medial elastocalcinosis. As vascular calcification is considered an independe...

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Detaylı Bibliyografya
Asıl Yazarlar: Schurgers, Leon J., Joosen, Ivo A., Laufer, Eduard M., Chatrou, Martijn L. L., Herfs, Marjolein, Winkens, Mark H. M., Westenfeld, Ralf, Veulemans, Verena, Krueger, Thilo, Shanahan, Catherine M., Jahnen-Dechent, Willi, Biessen, Erik, Narula, Jagat, Vermeer, Cees, Hofstra, Leonard, Reutelingsperger, Chris P.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2012
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3430691/
https://ncbi.nlm.nih.gov/pubmed/22952653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0043229
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