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Interferon Gamma and Sonic Hedgehog Signaling Are Required to Dysregulate Murine Neural Stem/Precursor Cells

BACKGROUND: The pro-inflammatory cytokine interferon gamma (IFNγ), a key player in various neurological diseases, was recently shown to induce a dysregulated phenotype in neural stem/precursor cells (NSPCs) that is characterized by the simultaneous expression of glial and neuronal markers and irregu...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Walter, Janine, Hartung, Hans-Peter, Dihné, Marcel
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3430684/
https://ncbi.nlm.nih.gov/pubmed/22952668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0043338
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