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A Novel Approach for Transcription Factor Analysis Using SELEX with High-Throughput Sequencing (TFAST)
BACKGROUND: In previous work, we designed a modified aptamer-free SELEX-seq protocol (afSELEX-seq) for the discovery of transcription factor binding sites. Here, we present original software, TFAST, designed to analyze afSELEX-seq data, validated against our previously generated afSELEX-seq dataset...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3430675/ https://ncbi.nlm.nih.gov/pubmed/22956994 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0042761 |
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