Association of cartilage-specific deletion of peroxisome proliferator-activated receptor γ with abnormal endochondral ossification and impaired cartilage growth and development in a murine model

OBJECTIVE: Long bones develop through the strictly regulated process of endochondral ossification within the growth plate, resulting in the replacement of cartilage by bone. Defects in this process result in skeletal abnormalities and can predispose to disease such as osteoarthritis (OA). Studies su...

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Main Authors: Monemdjou, Roxana, Vasheghani, Faezeh, Fahmi, Hassan, Perez, Gemma, Blati, Meryem, Taniguchi, Noboru, Lotz, Martin, St-Arnaud, René, Pelletier, Jean-Pierre, Martel-Pelletier, Johanne, Beier, Frank, Kapoor, Mohit
Format: Artigo
Sprog:Inglês
Udgivet: 2012
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3430604/
https://ncbi.nlm.nih.gov/pubmed/22131019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.33490
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