Llwytho...
The combination of olaparib and camptothecin for effective radiosensitization
BACKGROUND: Poly (ADP-ribose) polymerase-1 (PARP-1) is a key enzyme involved in the repair of radiation-induced single-strand DNA breaks. PARP inhibitors such as olaparib (KU-0059436, AZD-2281) enhance tumor sensitivity to radiation and to topoisomerase I inhibitors like camptothecin (CPT). Olaparib...
Wedi'i Gadw mewn:
| Prif Awduron: | , , , , , , |
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| Fformat: | Artigo |
| Iaith: | Inglês |
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BioMed Central
2012
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| Pynciau: | |
| Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3430568/ https://ncbi.nlm.nih.gov/pubmed/22524618 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1748-717X-7-62 |
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