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Parallel Genetic Changes and Nonparallel Gene–Environment Interactions Characterize the Evolution of Drug Resistance in Yeast

Beneficial mutations are required for adaptation to novel environments, yet the range of mutational pathways that are available to a population has been poorly characterized, particularly in eukaryotes. We assessed the genetic changes of the first mutations acquired during adaptation to a novel envi...

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Detalhes bibliográficos
Main Authors: Gerstein, Aleeza C., Lo, Dara S., Otto, Sarah P.
Formato: Artigo
Idioma:Inglês
Publicado em: Genetics Society of America 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3430539/
https://ncbi.nlm.nih.gov/pubmed/22714405
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.112.142620
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