How Do Heme-Protein Sensors Exclude Oxygen? Lessons Learned from Cytochrome c′, Nostoc puntiforme Heme Nitric Oxide/Oxygen-Binding Domain, and Soluble Guanylyl Cyclase

Significance: Ligand selectivity for dioxygen (O(2)), carbon monoxide (CO), and nitric oxide (NO) is critical for signal transduction and is tailored specifically for each heme-protein sensor. Key NO sensors, such as soluble guanylyl cyclase (sGC), specifically recognized low levels of NO and achiev...

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Autores principales: Tsai, Ah-lim, Martin, Emil, Berka, Vladimir, Olson, John S.
Formato: Artigo
Lenguaje:Inglês
Publicado: Mary Ann Liebert, Inc. 2012
Materias:
Forum Review Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3430480/
https://ncbi.nlm.nih.gov/pubmed/22356101
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ars.2012.4564
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