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Structural Insights into the Regulatory Mechanism of the Response Regulator RocR from Pseudomonas aeruginosa in Cyclic Di-GMP Signaling

The nucleotide messenger cyclic di-GMP (c-di-GMP) plays a central role in the regulation of motility, virulence, and biofilm formation in many pathogenic bacteria. EAL domain-containing phosphodiesterases are the major signaling proteins responsible for the degradation of c-di-GMP and maintenance of...

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Bibliografski detalji
Glavni autori: Chen, Ming Wei, Kotaka, Masayo, Vonrhein, Clemens, Bricogne, Gérard, Rao, Feng, Chuah, Mary Lay Cheng, Svergun, Dmitri, Schneider, Gunter, Liang, Zhao-Xun, Lescar, Julien
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2012
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3430337/
https://ncbi.nlm.nih.gov/pubmed/22753070
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.00560-12
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