The Functional Role of a Conserved Loop in EAL Domain-Based Cyclic di-GMP-Specific Phosphodiesterase

EAL domain-based cyclic di-GMP (c-di-GMP)-specific phosphodiesterases play important roles in bacteria by regulating the cellular concentration of the dinucleotide messenger c-di-GMP. EAL domains belong to a family of (β/α)(8) barrel fold enzymes that contain a functional active site loop (loop 6) f...

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Bibliographic Details
Main Authors: Rao, Feng, Qi, Yaning, Chong, Hui Shan, Kotaka, Masayo, Li, Bin, Li, Jinming, Lescar, Julien, Tang, Kai, Liang, Zhao-Xun
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 2009
Subjects:
Enzymes and Proteins
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2715702/
https://ncbi.nlm.nih.gov/pubmed/19376848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.00327-09
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