Genome-Wide Analysis of DNA Methylation and Expression of MicroRNAs in Breast Cancer Cells

DNA methylation of promoters is linked to transcriptional silencing of protein-coding genes, and its alteration plays important roles in cancer formation. For example, hypermethylation of tumor suppressor genes has been seen in some cancers. Alteration of methylation in the promoters of microRNAs (m...

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Autori principali: Morita, Sumiyo, Takahashi, Ryou-u, Yamashita, Riu, Toyoda, Atsushi, Horii, Takuro, Kimura, Mika, Fujiyama, Asao, Nakai, Kenta, Tajima, Shoji, Matoba, Ryo, Ochiya, Takahiro, Hatada, Izuho
Natura: Artigo
Lingua:Inglês
Pubblicazione: Molecular Diversity Preservation International (MDPI) 2012
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3430232/
https://ncbi.nlm.nih.gov/pubmed/22942701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms13078259
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