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RAD51 Mutants Cause Replication Defects and Chromosomal Instability
RAD51 is important for restarting stalled replication forks and for repairing DNA double-strand breaks (DSBs) through a pathway called homology-directed repair (HDR). However, analysis of the consequences of specific RAD51 mutants has been difficult since they are toxic. Here we report on the domina...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3430192/ https://ncbi.nlm.nih.gov/pubmed/22778135 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00406-12 |
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