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Chemical Modification and Irreversible Inhibition of Striatal A(2a) Adenosine Receptors

The ligand recognition site of A(2a)-adenosine receptors in rabbit striatal membranes was probed using non-site-directed labeling reagents and specific affinity labels. Exposure of membranes to diethylpyrocarbonate at a concentration of 2.5 mm, followed by washing, was found to inhibit the binding o...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: JACOBSON, KENNETH A., STILES, GARY L., JI, XIAO-DUO
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1992
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3429947/
https://ncbi.nlm.nih.gov/pubmed/1635550
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