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Acetylation and cleavage of purine nucleosides. Synthesis of 6-azauridine, 5-fluorouridine, and 5-methyluridine.

Inosine (I) when acetylated with acetic anhydride in the presence of acetyl chloride in acetic acid solution (the so called "acid acetylation"), affords an acetylated nucleoside III (75%) along with cleavage products of the nucleoside (hypoxanthine, 19%). The reaction of I with acetyl chlo...

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Bibliografiske detaljer
Main Authors: Beránek, J, Hrebabecký, H
Format: Artigo
Sprog:Inglês
Udgivet: 1976
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC342993/
https://ncbi.nlm.nih.gov/pubmed/940772
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