Effect of neonatal gene therapy on lumbar spine disease in mucopolysaccharidosis VII dogs

Mucopolysaccharidosis VII (MPS VII) is due to deficient β-glucuronidase (GUSB) activity, which leads to accumulation of chondroitin, heparan, and dermatan sulfate glycosaminoglycans in various tissues including those of the spine. Associated spine disease can be due to abnormalities in the vertebrae...

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Библиографические подробности
Главные авторы: Smith, Lachlan J, Martin, John T, O'Donnell, Patricia, Wang, Ping, Elliott, Dawn M, Haskins, Mark E, Ponder, Katherine P
Формат: Artigo
Язык:Inglês
Опубликовано: 2012
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3429794/
https://ncbi.nlm.nih.gov/pubmed/22510705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymgme.2012.03.013
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