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Model systems for studying trophoblast differentiation from human pluripotent stem cells
This review focuses on a now well-established model for generating cells of the trophoblast (TB) lineage by treating human embryonic stem cells (ESC) and induced pluripotent stem cells (iPSC) with the growth factor BMP4. We first discuss the opposing roles of FGF2 and BMP4 in directing TB formation...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Springer-Verlag
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3429771/ https://ncbi.nlm.nih.gov/pubmed/22427062 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00441-012-1371-2 |
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