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Model systems for studying trophoblast differentiation from human pluripotent stem cells

This review focuses on a now well-established model for generating cells of the trophoblast (TB) lineage by treating human embryonic stem cells (ESC) and induced pluripotent stem cells (iPSC) with the growth factor BMP4. We first discuss the opposing roles of FGF2 and BMP4 in directing TB formation...

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Detalhes bibliográficos
Main Authors: Ezashi, Toshihiko, Telugu, Bhanu Prakash V. L., Roberts, R. Michael
Formato: Artigo
Idioma:Inglês
Publicado em: Springer-Verlag 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3429771/
https://ncbi.nlm.nih.gov/pubmed/22427062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00441-012-1371-2
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