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Derivation of induced pluripotent stem cells from pig somatic cells

For reasons that are unclear the production of embryonic stem cells from ungulates has proved elusive. Here, we describe induced pluripotent stem cells (iPSC) derived from porcine fetal fibroblasts by lentiviral transduction of 4 human (h) genes, hOCT4, hSOX2, hKLF4, and hc-MYC, the combination comm...

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Detalhes bibliográficos
Main Authors: Ezashi, Toshihiko, Telugu, Bhanu Prakash V. L., Alexenko, Andrei P., Sachdev, Shrikesh, Sinha, Sunilima, Roberts, R. Michael
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2698893/
https://ncbi.nlm.nih.gov/pubmed/19541600
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0905284106
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