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Effect of CpG ODN on monocytic myeloid derived suppressor cells
CpG oligonucleotides stimulate via TLR9 and enhance anti-tumor immunity, an effect attributed to the activation of NK and CD8(+) T cells. Our recent work demonstrates that CpG ODN also induce monocytic myeloid-derived suppressor cells to mature into M1 macrophages, further aiding tumor elimination....
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Landes Bioscience
2012
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3429593/ https://ncbi.nlm.nih.gov/pubmed/22934281 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/onci.19731 |
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