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Development of a novel universal immune receptor for antigen targeting: To Infinity and beyond
Chimeric antigen receptors (CARs) possess fixed specificity for a single antigen and require empirical testing in T cells. To address this, we have developed a novel, adaptable immune receptor strategy that allows for the rapid generation and testing of T cells of nearly infinite antigen specificity...
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Landes Bioscience
2012
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3429592/ https://ncbi.nlm.nih.gov/pubmed/22934280 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/onci.19730 |
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