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Development of a novel universal immune receptor for antigen targeting: To Infinity and beyond

Chimeric antigen receptors (CARs) possess fixed specificity for a single antigen and require empirical testing in T cells. To address this, we have developed a novel, adaptable immune receptor strategy that allows for the rapid generation and testing of T cells of nearly infinite antigen specificity...

詳細記述

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書誌詳細
主要な著者: Urbanska, Katarzyna, Powell, Daniel J.
フォーマット: Artigo
言語:Inglês
出版事項: Landes Bioscience 2012
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3429592/
https://ncbi.nlm.nih.gov/pubmed/22934280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/onci.19730
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