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The downward spiral of tau and autolysosomes: A new hypothesis in neurodegeneration
A growing body of research has connected autophagy to neurodegenerative diseases such as Alzheimer disease (AD). In autopsied AD brain, large multivesicular bodies accumulate in neurons. Knockout mice deficient for key autophagy genes demonstrate age-dependent neurodegeneration. Most neurodegenerati...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Landes Bioscience
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3429552/ https://ncbi.nlm.nih.gov/pubmed/22635052 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.20515 |
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