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Interaction Between Eye Pigment Genes and Tau-Induced Neurodegeneration in Drosophila melanogaster

Null mutations in the genes white and brown, but not scarlet, enhance a rough eye phenotype in a Drosophila melanogaster model of tauopathy; however, adding rosy mutations suppresses these effects. Interaction with nucleotide-derived pigments or increased lysosomal dysregulation are potential mechan...

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Autors principals: Ambegaokar, Surendra S., Jackson, George R.
Format: Artigo
Idioma:Inglês
Publicat: Genetics Society of America 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2940309/
https://ncbi.nlm.nih.gov/pubmed/20592261
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.110.119545
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