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MAPK14/p38α confers irinotecan resistance to TP53-defective cells by inducing survival autophagy
Recently we have shown that the mitogen-activated protein kinase (MAPK) MAPK14/p38α is involved in resistance of colon cancer cells to camptothecin-related drugs. Here we further investigated the cellular mechanisms involved in such drug resistance and showed that, in HCT116 human colorectal adenoca...
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| 主要な著者: | , , , , , , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Landes Bioscience
2012
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3429546/ https://ncbi.nlm.nih.gov/pubmed/22647487 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.20268 |
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