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Targeting pre-miRNA by Peptide Nucleic Acids: A new strategy to interfere in the miRNA maturation
PNAs conjugated to carrier peptides have been employed for the targeting of miRNA precursor, with the aim to develop molecules able to interfere in the pre-miRNA processing. The capability of the molecules to bind pre-miRNA has been tested in vitro by fluorescence assayes on Thiazole Orange labeled...
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| Главные авторы: | , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Landes Bioscience
2012
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3429535/ https://ncbi.nlm.nih.gov/pubmed/22699795 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/adna.20911 |
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