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Positive selection of co-opted mobile genetic elements in a mammalian gene: If you can’t beat them, join them

The proopiomelanocortin (Pomc) gene encodes a prepropeptide with essential functions in the response to stress and energy balance, which is expressed in the pituitary and hypothalamus of vertebrate animals. Neuronal expression of Pomc is controlled by two distal enhancers named nPE1 and nPE2. Using...

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Bibliografske podrobnosti
Main Authors: Franchini, Lucia F., de Souza, Flavio S.J., Low, Malcolm J., Rubinstein, Marcelo
Format: Artigo
Jezik:Inglês
Izdano: Landes Bioscience 2012
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3429518/
https://ncbi.nlm.nih.gov/pubmed/22934245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/mge.20267
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