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Positive selection of co-opted mobile genetic elements in a mammalian gene: If you can’t beat them, join them

The proopiomelanocortin (Pomc) gene encodes a prepropeptide with essential functions in the response to stress and energy balance, which is expressed in the pituitary and hypothalamus of vertebrate animals. Neuronal expression of Pomc is controlled by two distal enhancers named nPE1 and nPE2. Using...

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Detalhes bibliográficos
Main Authors: Franchini, Lucia F., de Souza, Flavio S.J., Low, Malcolm J., Rubinstein, Marcelo
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3429518/
https://ncbi.nlm.nih.gov/pubmed/22934245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/mge.20267
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